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Hepagen-C (canine) 90 chews
Hepagen-C (canine) 90 chews
Hepagen-C (canine) 90 chews

Hepagen-C (canine) 90 chews

$37.00 Add Review
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Thorne Veterinary Hepagen-C (canine) 90 chews

Thorne Research Veterinary Hepagen-C (Canine)

Hepagen-C (Canine) 90 chews is available by Thorne Research Veterinary.

small animal hepatic support

  • protect hepatic cells
  • promote phase I and II detoxification
  • support normal glutathione levels

Product Information

Because of the toxic effects of food, water, and the environment, the liver can be a very busy organ, for humans as well as companion animals. Hepagen-C combines the beneficial liver herbs milk thistle and curcumin (from turmeric) with antioxidants and important nutrients for phase I and II liver detoxification. Pyridoxal 5'-phosphate acts as a cofactor for enzymes, catalyzes reactions with amino acids, and aids in the synthesis of nonessential amino acids. In this formula, the active form of vitamin B6, pyridoxal 5'-phosphate, is provided because normal liver function is necessary of activation of vitamin B6. Vitamin B12 is required for proper digestion and absorption of food. It is also utilized in amino acid digestion as well as carbohydrate and fat metabolism.

Dimethylglycine (DMG) is a derivative of glycine, the simplest amino acid. It is a building block for many important substances, including methionine and choline. Choline citrate is a lipotropic factor essential to the lipid layer of cell membranes. It helps regulate the gallbladder and is used extensively in the liver to move fats in and out of the cells. It is required for formation of the hepatic cell membrane component phosphatidylcholine and the neurotransmitter acetylcholine. Methionine is an essential sulfur-containing amino acid necessary for phase II detoxification. It helps metabolize fats and is a precursor to cysteine and taurine synthesis. It can be converted to cysteine, a component of glutathione, an important endogenous antioxidant.

N-acetylcysteine (NAC) is composed of the amino acid cysteine and a sulfhydryl group, enabling it to interact with disulfide bonds. NAC serves as a nutritional precursor for the synthesis of glutathione. Reduced glutathione is an important endogenous antioxidant, essential for liver detoxification. alpha-Lipoic acid is a powerful antioxidant that enhances the antioxidant effects of vitamins C and E and glutathione. alpha-Lipoic acid induces a substantial increase in cellular reduced glutathione by enabling the key enzyme of glutathione synthesis, gamma-glutamylcysteine synthetase. It is an antioxidant in both fat- and water-soluble tissues and in both its reduced and oxidized forms.

Silybum marianum (milk thistle) contains several potent flavolignans, including three structural isomers, silybin, silydianin, and silychristin, collectively referred to as silymarin. The antioxidant activity of silymarin appears to stabilize hepatocyte membranes, neutralize free radicals, and maintain liver glutathione levels.


Active Ingredients Per Capsule:

Methionine 100 mg.
N-Acetyl-L-Cysteine 100 mg.
Dimethylglycine (DMG) 50 mg.
Milk Thistle extract (Silybum marianum) 50 mg.
Turmeric extract (Curcuma longa) 50 mg.
Choline Citrate 20 mg.
Alpha Lipoic Acid 10 mg.
Pyridoxal 5'-Phosphate 5 mg.
Vitamin B12 50 mcg.

Other Ingredients: Natural bacon flavoring.

Contains ingredient derived from soy.

Serving Size

Suggested Use

Dogs (all): Two capsules for every 50 lbs body weight as needed.

Recommended for promoting liver detoxification.


For use in dogs only.

Safe use in pregnant animals or animals intended for breeding has not been proven. If animal's condition worsens or does not improve, stop product administration and consult your veterinarian. Not to be used if nursing. May be a GI irritant.

For animal use only. Keep out of the reach of children and other animals. In case of accidental overdose, contact a health professional immediately.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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