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Manufacturer: Douglas Labs Product Description:Ayur-Coleus forskohlii (250mg) 60c is available by Douglas Laboratories. Ayur-Coleus Forskohlii A Dietary Supplement
Douglas
Laboratories® 100 Capsules More Info:
Ayur-Coleus Forskohlii, provided by Douglas Laboratories, contains 250 mg of Coleus forskohlii leaf extract, standardized to contain a minimum of 1% forskolin. Ayur-Coleus Forskohlii may be a useful dietary adjunct for individuals who wish to supplement their diet Coleus forskohlii. In its native India, coleus has been used in the ancient medical system of Ayurveda for centuries. Ayurvedic traditions recommend coleus to aid the health of the heart, respiratory system, and digestive tract, among other uses. Coleus forskohlii is the only plant known to contain the diterpenoid forskolin. Forskolin activates adenylate cyclase, which in turn activates cyclic adenosine monophoshate (cAMP), an intracellular second messenger responsible for inducing the cellular response to hormonal activation. Because forskolin effectively activates cAMP, it has been used in numerous research studies to explore the mechanisms and effects of cAMP. Within the body, hormones bind to extracellular membrane receptors on their target cells. Following hormone-receptor binding, adenylate cyclase is activated from the inner cellular membrane. Adenylate cyclase catalyzes the conversion of adenosine triphosphate (ATP) to cAMP. This conversion fosters the activation of cAMP-dependent enzymes. The cAMP-dependent enzymes in turn activate or inhibit the specific enzymes within the cell, thereby eliciting the response associated with the binding hormone. Catecholamines, adrenocorticotropic hormone, and vasopressin are among the many hormones that elicit action via the cAMP second messenger system. Forskolin activates adenylate cyclase, thereby increasing cAMP levels without direct hormonal stimulation. By activating cAMP, forskolin can direct the activation of the many, diverse cAMP-activated enzymes. Laboratory and clinical studies have documented several benefits of forskolin. Forskolin has cardiac inotropic properties in that it appears to help strengthen heart muscle contractability. Forskolin promotes vasodilation, thereby decreasing peripheral vascular resistance. Compounds in coleus including, but not limited to, forskolin, provide further benefit to the cardiovascular system by inhibiting platelet aggregating factor. Forskolin has also been shown to promote bronchodilation, in part by helping to relax airway smooth muscles and by inhibiting histamine and leukotriene release. Ingredients:Serving Size: 1 capsule
Servings Per Container: 60 Amount Per Serving
Coleus forskohlii ...250mg*
(root)
(standardized to 1% forskohlin) * Daily Value not established Contains:
Gelatin (capsule) and vegetable stearate Does Not Contain:
yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring Dosage:Suggested Usage:
As a dietary supplement, adults take 1 capsule twice daily or as directed by physician. WARNINGS:KEEP OUT OF REACH OF CHILDREN. For optimal storage conditions, store in a cool, dry place.
(59 ° - 77 ° F / 15 ° - 25 ° C) (35-65% relative humidity)
Tamper resistant package, do not use if outer seal is missing.
About Douglas Labs
Douglas Laboratories is the part of the Atrium Biotechnologies group of companies and is a global leader in the development, manufacturing, and marketing of dietary supplements, specialty fine chemicals, and active cosmetic ingredients.
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